Hirschsprung's Disease
Plain X-ray showed marked dilatation of sigmoid colon and rectum
Plain X-ray showed marked dilatation of sigmoid colon and rectum, the ground glass appearance of retained fecal material in the dilated bowel loop is noted

Barium enema showed contracted diseased segment (thick arrow), dilatation of normal bowel segment (thin arrow) and the transitional zone (TZ)

Barium enema showed contracted diseased segment, dilatation of normal bowel segment and the transitional zone at upper rectum

Barium enema showed contracted diseased segment, dilatation of normal bowel segment and the transitional zone at sigmoid colon

Barium enema showed contracted diseased segment, dilatation of normal bowel segment and the transitional zone at mid-rectum (lower arrow) and jejunization of the colon (upper rectum)
Manometry and manography is one of investigations for Hirschsprung's disease

In manometry, the transducers are placed at various level of rectum to determine the pressure in each part during peristalsis
Graph of the pressure in various parts of rectum
Graph of the pressure at internal sphincter level , left graph is normal showing contraction and relaxation but right graph shows no relaxation (reflex relaxation) indicating Hirschsprung's disease