Course Map: Epithelial Tumors: Malignant: Urothelial Carcinoma: Variants of Urothelial Carcinoma: Nested Variant

Nested Variant
These carcinomas infiltrate as small, rounded cell aggregates which resemble nests of von Brunn. It differs from benign nests, however, in that they show more variation in size and contour and some mild nuclear atypia [40,76,81].
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	Figure 1: Urothelial carcinoma, nested variant, grade I infiltrating lamina propria (pT1). Note that the tumor nests have varied shapes.
	Figure 2: This is a different case with the same diagnosis. The cytokeratin immunostain highlights the tumor morphology.