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CARCINOMA OF THE STOMACH

MORPHOLOGIC VARIANTS OF GASTRIC ADENOCARCINOMA

Gastric Carcinoma with Rhabdoid Features

This is a recently described rare variant of gastric carcinoma with a poor prognosis. The tumor has a diffuse or alveolar arrangement and is composed of round to polygonal tumor cells with eosinophilic or clear cytoplasm and large eccentric vesicular nuclei similar to those seen in malignant rhabdoid tumors of the kidney. In all cases, there was coexpression of vimentin and cytokeratin in the cytoplasm (252).

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