EDUCATION

• 2001(2 weeks) Foreign Animal Disease Diagnosticians Training Course, US Department of Agriculture, Plum Island, NY
• 1990-1993 Residency, Veterinary Pathology, Armed Forces Institute of Pathology
• 1989-1990 Master of Military Art and Science, United States Army Command and General Staff College
• 1978-1982 Doctor of Veterinary Medicine, with honor, Colorado State University
• 1976-1978 Master of Science, Animal Nutrition, Oklahoma State University
• 1974-1976 Bachelor of Science, Agriculture, Purdue University

BOARD CERTIFICATION

• 1996 Veterinary Pathologist, The American College of Veterinary Pathologists
• 1988 Veterinary Preventive Medicine, The American College of Veterinary Preventive Medicine

STATE LICENSES

• Utah 1983 - Present
• Texas 1983 - Present

HONORS

• Army Meritorious Service Medal, 2nd Oak Leaf Cluster, 1999
• Army Meritorious Service Medal, 1st Oak Leaf Cluster, 1989
• Army Meritorious Service Medal, 1986
• Army Commendation Medal, 1983
• Member of Outstanding Young Men of America, 1983
• Member of Phi Zeta, National Veterinary Honor Society, 1982
• Awarded Health Professions Scholarship in Veterinary Medicine by the US Army in 1978
• Member of American Animal Science Society Scholarship Program, 1975, 1976
• Member of Society of Gamma Sigma Delta, National Honor Society of Agriculture, 1975
• Awarded the Utah Veterinary Medical Association Scholarship, 1969

PROFESSIONAL SOCIETIES

• American Veterinary Medical Association
• American College of Veterinary Preventive Medicine
• American College of Veterinary Pathologists
• Society of Toxicologic Pathologists

PROFESSIONAL EXPERIENCE

Research Background:

Two and one-half years applied and basic rumenology, with wheat pasture and soil analysis (1976-78).

Mammalian Toxicology Branch, Division of Toxicology, Letterman Army Institute of Research, Presidio of San Francisco, CA. Nov 1986 to Jun 1989, applied GLP mammalian toxicology bench experience. Project officer for 30 protocols, Principal Investigator or Co-Principal Investigator on 21 studies.

Division of Pathology, Walter Reed Army Institute of Research, Washington, D.C. August 1993 to May 1999, involved in the development of toxoid vaccines to counter potential aerosol attacks on military personnel, to include management of pre-clinical trials designed to select vaccine candidates for advanced development.

Department of Pathology, Armed Forces Institute of Pathology, Washington, DC. May 1999 to present. Provide and coordinate the pathology requirements for the animal biomedical research mission of the Institute. Manages the department consultative, educational and research missions in environmental and toxicological pathology and works with the AFIP Center for Environmental and Toxicological Pathology. Serves as Chief, Research Branch and Director, Registry of Toxicologic Pathology for Animals (RTPA). Serves as investigator/co-investigator on Institute research protocols. Provides expertise and training in toxicologic pathology and research.

Administrative Background:

ADPAC VCO and Fund Custodian for Randolph and Berkstrom AFB 1982-83. Supervised four animal technicians (91T) and three civilians.

Deputy Commander for Veterinary Activities, SHAPE MEDDAC, Commander of the 79th Medical Detachment, VS, JA, NAFI Fund Manager and Contracting Officer for the Benelux Animal Care Fund, SHAPE, Belgium, Oct 83 - Nov 86. Supervised 2 91Ts, 10 food inspectors (91R) and 15 civilians.

Branch Chief, Mammalian Toxicology, Division of Toxicology, Letterman Army Institute of Research, Presidio of San Francisco, CA; Jul 87 - Jul 89. Supervised 3 professional investigators, 4 technicians and 5 animal caretakers. The assignment at Letterman Army Institute of Research included the following duties: Served as Branch Chief and Principal Investigator for classical mammalian toxicological studies conducted in compliance with the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) Good Laboratory Practice (GLP) regulations. Supervised the development of additional chronic toxicological testing capabilities. Trained technicians in procedures for making medical observations on test animals, recording data and conducting toxicological testing procedures. Utilized and evaluated automated data collection systems (TOXSYS® and XYBION®). Prepared protocols, standard operating procedures (SOP), and reports in compliance with GLP specifications. Inspected toxicology animal suites to ensure humane care of animals and compliance of studies with GLP requirements. Conducted tours for visiting dignitaries.

Resident, Division of Veterinary Pathology, Armed Forces Institute of Pathology, Washington, D.C; Jul 90 - Jul 93. Principle duties were as follows: performed necropsies and histopathological examinations on military-owned animals, laboratory animals, and other animal specimens submitted by military and civilian pathologists for consultation; researched professional literature and presents written and oral presentations at weekly pathology seminars; prepared and published case reports in scientific journals; served as the Department Library Officer; served as a prosector at the National Zoological Park; attended short courses and academic courses as required by the training officer; prepared for the American College of Veterinary Pathology certifying examination.

Chief, Department of Diagnostic Pathology, 1994-1997. Directed and managed scientific and fiscal operations of a lead Army Medical Department vaccine development laboratory, to include development of advanced approaches to biological defense against a major biological warfare agent. Performed administrative functions as Contracting Officer's Representative for a $650K collaborative research program to include the mapping of essential molecular toxin domains, peptide vaccine development and efficacy testing of these innovative vaccines in animal models. Supervised the professional development of 8 personnel. Performed duties as Staff Pathologist.

Chief, Department of Comparative Pathology, 1997-1999. Performed administrative functions to manage and directed a department with 3 branches providing histopathology, bacteriology, necropsy and clinical pathology support to the Army's largest biomedical research institute and the Department of Defense's lead agency of infectious disease research. Served as Team Leader of a multi-disciplined group of bioengineers, physicians, statisticians, biochemists, toxinologists, immunologists, bacteriologists, veterinarians and behavioral psychologists to accomplish collaborative inter-institutional research protocols designed to protect soldiers against a major biological threat agent. Supervised the duties of pathologists, biologists, chemists, technicians and contractors. Developed, executed and directed collaborative clinical and anatomic pathological support for the institute's research protocols. Served as member of institute's Editorial Board.

Description of Current Duties:

Serves as both Chief, Research Branch, Department of Veterinary Pathology, Armed Forces Institute of Pathology, Lieutenant Colonel, U.S. Army, and Director of the Registry of Toxicologic Pathology for Animals (RTPA), to include management of the RTPA's Web conferences. Also a member of the teaching staff of AFIP's Veterinary Pathology Residency program and Institute Institutional Animal Care and Use Committee.

PUBLIC RELATIONS EXPERIENCE

• Presiding ecclesiastical authority with responsibility for over 550 people, 1992 - 1999
• Scout Master, Troop 1660, 1991-1992
• Missionary, Bolivia, 1970-1972; labored among the Quechua Indians proselytizing, teaching sanitary hygiene and modern agriculture techniques
• Foreign languages spoken:
  Spanish, South American
  Spanish, Castillian
  Quechua
  German

SPECIAL INTERESTS/HOBBIES

Reading, cross country running, hiking, nutrition, shaving, languages, anthropology

PUBLICATIONS

Masters Theses:

Frost, DF, 1978: Ruminal Motility and Bloat Potential of Wheat Pasture Stockers; Oklahoma State University.

Frost, DF, 1990: A Centralized Source of Information for the Military Working Dog Program; U.S. Army Command and General Staff College.

Papers/Abstracts/Selected Presentations:

1. Horn, GW and Frost, DF: Ruminal Motility of Stocker Cattle Grazed on Winter Wheat Pasture. In: Journal of Animal Science, Vol. 55, No. 4, 1982.
2. Frost, DF and Horn, GW: Ruminal Motility and Bloat Potential of Wheat Pasture Stockers. In: Joint Annual Meetings of the American Dairy Science Association and American Society of Animal Science, July 19, 1978.
3. Bowman P, Schuschereba S, Johnson T, McKinney L, Wheeler C, and Frost D. Myopathic Changes in Rat Diaphram Induced by Pyridostigmine Bromide (abstract F-48, 2884). In: Proceedings of 72nd Annual Meeting of the Federation of American Societies for Experimental Biology, (1-5 May) 1988: 114.
4. Frost DF, Brown LD, Morgan EW, and Korte DW. Acute Toxicity of Diethyleneglycol Dinitrate (DEGDN) and Two DEGDN - Containing Solid Propellants, DIGL-RP and JA-2. IN: JANNAF Safety and Environmental Protection Subcommittee Meeting, Naval Post Graduate School, Monterey, CA, 23-26, May 1988.
5. Korte DW, Frost DF, Zaucha GM, Waring PP, Clifford CB, Wheeler CR. 28-Day Subcutaneous Toxicity of Physostigmine in Beagle Dogs. IN: Thirty-Second Annual Meeting of the Western Pharmacology Society, Jan 1989. Poster Session.
6. Frost DF, Omaye ST, Zaucha GM, Clifford, CB, Wheeler, CR, Schuschereba ST, Korte DW. Subcutaneous Toxicity of Physostigmine Salicylate Administered Continuously to Rats Via 28 - Day Alset® Minipumps. In: Proceedings of the 28th Annual Meeting of the Society of Toxicology, February 1989. Abstract Number 1018.
7. Zaucha GM, Frost DF, Young GD, Korte DW. Local Irritation Potential of Hypertonic Saline/Dextran 70® in Rabbits. In: Proceedings of the 28th Annual Meeting of the Society of Toxicology, February 1989. Abstract Number 971.
8. Zaucha, GM, Frost DF, Young GD, and Korte DW. Local Irritation Potential of Hypertonic Saline/Dextran 70® in Rabbits. In: The Toxicologist, Vol. 9, No. 1, February/March 1989.
9. Frost DF, Omaye ST, Zaucha GM, Clifford CB, Wheeler CR, Schuschereba ST, and Korte DW. Subcutaneous Toxicity of Physostigmine Salicylate Administered Continuously in Rats Via 28-Day Alset® Minipumps. In: The Toxicologist, Vol. 9, No. 1, February/March 1989.
10. Zaucha GM, Lewis CM, Morgan EW, Makovec GT, Frost DF, Smith CD, and Korte, DW. Ninety-Day Subchronic Oral Toxicity Study of Nitroguanidine in Rats and Mice. In: 1989 JANNAF Safety and Environmental Protection Subcommittee Meeting, Brooks Air Force Base, San Antonio, TX, April 1989.
11. Korte DW, Frost DF, and Zaucha GM. Intravenous Toxicity of a Hypertonic Saline/Dextran 70® Resuscitation Fluid. In: The Pharmacologist, Vol. 31, No. 3, 1989.
12. Korte DW, Frost DF, Zaucha GM, Waring PP, Clifford CB, and Wheeler CR. Twenty-Eight Day Toxicity in Beagle Dogs of Physostigmine Salicylate Administered Via Subcutaneously Implanted Alset® Osmotic Minipumps. In: Proc. West. Pharmacol. Soc., 32:159, 1989.
13. Summary JJ, Ryan BA, Dubick MA, Frost DF, Zaucha GM, Wade CE and Korte DW. Serum Immunoglobulin and Complement Responses to 7.5% Saline-6% Dextran in Pigs and Dogs. Abstract presentation at the NorCal Society of Toxicology Meeting, May, 1989.
14. Bowman P, Schuschereba S, Johnson T, McKinney L, Wheeler C, and Frost D. Myopathic Changes in Diaphram of Rats Fed Pyridostigmine Bromide Subchronically. In: Journal of Fundamental and Applied Toxicology, Volume 13, No. 1, July 1989.
15. Omay ST, Zaucha GM, Frost DF, Clifford CB, McKinney LA, and Korte DW. Subacute Intravenous Toxicity of a Hypertonic Saline Dextran 70® Resuscitation Fluid. In: The Toxicologist, Vol 10, No. 1, February 1990.
16. Zaucha GM, Orner GA, Frost DF, Omaye ST, and Korte, DW. Micronucleus Assay of Physostigmine Salicylate in Rats and Dogs. In: The Toxicologist, Vol. 10, No. 1, February 1990.
17. Korte DW, Frost DF, Zaucha GM. Acute Intravenous (IV) Toxicity of Hypertonic Saline/Dextran 70® (HSD) Resuscitation Fluid. Abstract submitted for: American Society of Pharmacology and Experimental Therapeutics. 1989 Annual Meeting (August).
18. Omaye ST, Zaucha GM, Frost DF, Clifford CB, McKinney LA, and Korte DW, Jr. Subacute Intravenous (IV) Toxicity of a Hypertonic Saline/Dextran 70® (HSD) Resuscitation Fluid. In: Proceedings of the 29th Annual Meeting of the Society of Toxicology, February 1990. Abstract.
19. Zaucha GM, Orner GA, Frost DF, Omaye ST, and Korte DW, Jr. Micronucleus Assay of Physostigmine Salicylate in Rats and Dogs. In: Proceedings of the 29th Annual Meeting of the Society of Toxicology, February 1990. Abstract.
20. Swearengen JR, Miller GF, Frost DF and Davis JA. Clinical signs of Concomitant Renal and Cardiac Disease in an Owl Monkey. Proceedings of the Annual Meeting of the American Veterinary Medical Association, July 1992. Poster Session.
21. Frost DF, Nichols DK and Citino SB. Gastric Cryptosporidiosis in Two Ocellated Lacertas. Proceedings of the Annual Meeting of the American Association of Zoo Veterinarians, November 1992. Poster Session.
22. Frost DF, Nichols DK and Citino SB. Gastric Cryptosporidiosis in Two Ocellated Lacertas (Lacerta lepida). In: Journal of Zoo and Wildlife Medicine, Vol. 25, No. 1, March 1994.
23. Lowell GH, Kaminski R, Colleton C, Mallett C, Orr N, Anselem S, Noel J, Estep J, Pitt L, Kersey K, Hughes M, Vancott T, Baker W, Frost D, Hunt R, Cohen D, Arnon R, Smith G, Redfield R, Birx D, Hale T, Baze W. Proteosomes and PA Adjuvants Enhance Mucosal Immunogenicity and Efficiacy of HIV, Shigella, and Staphylococcal Enterotoxin B Vaccines. Proceedings of Annual Meeting of Molecular Approaches to the Control of Infectious Diseases, October 1994.
24. Lowell GH, Kaminski R, Mallett C, Anselem S, Orr N, Noel J, Hughes M, Levi M, Kersey K, Hartmann A, Pitt L, Colleton C, Mullett C, Frost D, Baker W, Loomis L, Grate S, Hunt R, Cohen D, Arnon R, Wahren B, Acheson D, Escheverria P, Boedeker E, Smith G, Redfield R, Birx D, Hale T, Baze W. Respiratory or Parenteral Vaccines with Proteosomes and/or PA: Induction of Mucosal and Systemic Immunity and Protection in Rodent and Monkey Models of Staphylococcal Enterotoxin B Intoxication, Shigellosis, Enterohemorrhagic E. Coli or HIV. Proceedings of the Annual Meeting of the International Society for Vaccines, May 1994.
25. Lowell G, Kaminski R, Colleton C, Mallett C, Orr N, Amselem S, Estep J, Pitt L, Kersey K, Hughes M, Vancott T, Baker W, Frost D, Hunt R, Cohen D, Arnon R, Smith G, Redfield R, Brix D, Hale T, and Baze W. Proteosomes and PA Adjuvants Enhance Mucosal Immunogenicity and Efficacy of HIV, Shigella, and Staphylococcal Entertotoxin B Vaccines. Proceedings of the Annual Meeting on Molecular Approaches to the Control of Infectious Diseases, October 1994.
26. Baze WB, Colleton C, Baker W, Frost D, Hunt R, Topper M, Lowell G. Toxoid-Proteosome Vaccine Protects Against Lethal Aerosol Staphylococcal Enterotoxin B Challenge. Eighth International Congress of Mucosal Immunity, July 1995. Poster Session.
27. Asher LVS, Colleton CA, Tseng J, Frost D, Nossov P, Baker WH, Topper M, Hunt R, and Baze WB. Absence of Apoptosis in Peripheral Blood Mononuclear Cells of Monkeys Immunized with Formalinized SEB Toxoid Vaccines. Proceedings of the 1996 Medical Defense Bioscience Review, May 1996. Poster Session.
28. Tseng J, Trout RN, Komisar JL, Colleton C, Baze WB, Frost D, Essiet I, Baumgartner R, and Nossov PC. A Comparison Study of Three New Staphylococcal Entertotoxin B (SEB) Vaccine Candidates: SEB-toxoid, SEB-toxoid Containing Microspheres, and SEB-toxoid Formulated Proteosomes. Proceedings of the 1996 Medical Defense Bioscience Review, May 1996. Poster Session.
29. Frost DF. Staphlycoccal Enterotoxin B - Vaccine Development. Platform Presentation, American Veterinary Medical Association Annual Convention, July 1996.
30. Lowell GH, Colleton C, Frost D, Kaminski RW, Hughes M, Hatch J, Hooper C, Estep J, Pitt L, Topper M, Hunt RE, Baker W and Baze WB. Immunogenicity and Efficiacy against Lethal Aerosol Staphylococcal Enterotoxin B Challenge in Monkeys by Intramuscular and Respiratory Delivery of Proteosome-Toxoid Vaccines. Infection and Immunity, Vol 64, No. 11: 4686-4693, November 1996.
31. Frost, DF. The Role of Staphylococcal Enterotoxins (SE's) in Public Health and Concerns About Their Potential Use as Biological Weapons. Platform Presentation, American Veterinary Medical Association Annual Convention, July 1997.
32. Frost, DF. Using a Non-Human Primate Model of Soldier Performance to Assess Incapacitation Following Exposure to a Biological Threat, Platform Presentation, 105th Annual Meeting of the Association of Military Surgeons of the United States. November 1998.
33. Frost, DF. Morphologic, Immunohistochemical and Molecular Genetic Characterization of a Gastric Stromal Tumor in a Chimpanzee (Pan troglodytes), Case Presentation, The Non-human Primate Pathology Seminar and Workshop, October 2000.
34. Frost DF, Abbott C, Eastep J, Richman M and Inskeep W. On-line Conferencing - Removing the Barriers of Time, Cost and Distance to Create a New Type of Histopathology Conference. Platform Presentation and Panel Discussion, American College of Veterinary Pathologists, December 2000.

Technical Reports:

1. Frost, DF and Horn GW: Frothy Bloat in Stocker Calves. In: Journal Article 3840 of the Agr. Exp. Sta., Oklahoma State University, Stillwater 74078, October 1977.
2. *Tox 129 Institute Report, Acute Oral Toxicity (MLD) of Nitroguanidine in Rats. Earl W. Morgan, DVM, MAJ, VC, Denzil F. Frost, MS, DVM, CPT, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 84034.
3. *Tox 130 Institute Report, Acute Oral Toxicity of Ball Powder® in ICR Mice. Gerald F. S. Hiatt, PhD, DAC, Denzil F. Frost, MS, DVM, CPT, VC, Conrad Wheeler, PhD, DAC, and Don W. Korte, Jr., PhD, LTC, MSC. GLP Study 84035.
4. *Tox 168 Institute Report, Acute Oral Toxicity (MLD) of Nitrosoguanidine in Rats. Earl W. Morgan, DVM, MAJ, VC, Denzil F. Frost, MS, DVM, CPT, VC, and Don W. Korte, Jr, PhD, MAJ, MSC. GLP Study 85008.
5. *Tox 169 Institute Report, Acute Oral Toxicity (MLD) Of Nitrosoguanidine in Mice. Earl W. Morgan, DVM, MAJ, VC, Denzil F. Frost, MS, DVM, CPT, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 85009.
6. *Tox 173 Institute Report, Dermal Sensitization Potential of Nitrosoguanidine in Guinea Pigs. Earl W. Morgan, DVM, MAJ, VC, Denzil F. Frost, MS, DVM, CPT, VC and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 85013.
7. *Tox 175 Institute Report, Primary Dermal Irritation Potential of JA-2 Propellant in Rabbits. Earl W. Morgan, DVM, CPT, VC, Denzil F. Frost, MS, DVM, CPT, VC and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 85019.
8. *Tox 200 Institute Report, Ninety-Day Subchronic Oral Toxicity Study of Nitroguanidine in Mice. Denzil F. Frost, MS, DVM, CPT, VC, Earl W. Morgan, DVM, MAJ, VC, Yvonne Letellier, BS, Michael J. Pearce, MA, Suellen Ferraris, PhD, C. Dahlem Smith, DVM, MAJ, VC, Gary M. Zaucha, DVM, CPT, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 86007.
9. *Tox 202 Institute Report, Dermal Sensitization Potential of a Schistosome Topical AntiPenetration Lotion in Guinea Pigs. Denzil F, Frost, MS, DVM, CPT, VC, Dean K. Magnuson, BS, SP4 and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 87016.
10. *Tox 214 Institute Report, Acute Subcutaneous Toxicity of Physostigmine Salicylate in Sprague-Dawley Rats. Denzil F. Frost, MS, DVM, CPT, VC, Earl W. Morgan, DVM, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 87005.
11. *Tox 216 Institute Report, Acute Subcutaneous Toxicity of Physostigmine Salicylate in ICR Mice. Denzil F. Frost, MS, DVM, CPT, VC, Earl W. Morgan, DVM, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 87007.
12. *Tox 217 Institute Report, Acute Oral Toxicity of Physostigmine Salicylate in Guinea Pigs. Denzil F. Frost, DVM, CPT, VC, Earl W. Morgan, DVM, MAJ VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 87008.
13. *Tox 220 Institute Report, Twenty-Eight Day Subcutaneous Subchronic Toxicity of Physostigmine Salicylate in Rats. Denzil F. Frost, MS, DVM, CPT, VC, Stanley T. Omaye, PhD, Gary M. Zaucha, DVM, CPT, VC, Charles B. Clifford, DVM, PhD, MAJ, VC, Conrad R. Wheeler, PhD, Steven T. Schuschereba, MS, Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 87011.
14. *Tox 224 Institute Report, Twenty-Eight Day Subchronic Toxicity Study of Physostigmine Salicylate in Beagle Dogs. Denzil F. Frost, MS, DVM, CPT, VC, Robert D. Hall, DVM, COL, VC, Gary M. Zaucha, DVM, CPT, VC, Paul P. Waring, BS, Charles B. Clifford, DVM, PhD, MAJ, VC, Conrad R. Wheeler, PhD, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 87013.
15. *Tox 233 Institute Report, Dermal Sensitization Potential of Niclosamide in Guinea Pigs. Denzil F. Frost, MS, DVM, CPT, VC, Gary M. Zaucha, DVM, CPT, VC, Robert E. Harris, DVM, CPT, VC, C. Dahlem Smith, DVM, MAJ, DVM, Conrad R. Wheeler, PhD, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 88005.
16. *Tox 244 Institute Report, Local Irritation Toxicity Study of Hypertonic Saline/Dextran 70® and its Constituents in New Zealand White Rabbits. Denzil F. Frost, MS, DVM, CPT, VC, Gary M. Zaucha, DVM, CPT, VC, G. David Young, DVM, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 88004.
17. *Tox 245 Institute Report, Acute Intravenous Toxicity Study of Hypertonic Saline/Dextran 70® and its Constituents in ICR Mice. Denzil F. Frost, MS, DVM, CPT, VC, Gary M. Zaucha, DVM, CPT, VC, G. David Young, DVM, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 88001.
18. *Tox 246 Institute Report, Acute Intravenous Toxicity Study of Hypertonic Saline/Dextran 70® and its Constituents in New Zealand White Rabbits. Gary M. Zaucha, DVM, CPT, VC, Denzil F. Frost, MS, DVM, CPT, VC, Luann McKinney, DVM, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 88002.
19. *Tox 247 Institute Report, Acute Intravenous Toxicity Study of Hypertonic Saline/Dextran 70® and its Constituents in Dogs. Denzil F. Frost, MS, DVM, CPT, VC, Gary M. Zaucha, DVM, CPT, VC, Charles B. Clifford, DVM, PhD, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 88003.
20. *Tox 248 Institute Report, Subchronic Intravenous Toxicity Study of Hypertonic Saline/Dextran 70® and its Constituents in New Zealand White Rabbits. Gary M. Zaucha, DVM, CPT, VC, Denzil F. Frost, MS, DVM, CPT, VC, Charles B. Clifford, DVM, PhD, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 88010.
21. *Tox 249 Institute Report, Subchronic Intravenous Toxicity Study of Hypertonic Saline/Dextran 70® and its Constituents in Dogs. Denzil F. Frost, MS, DVM, CPT, VC, Gary M. Zaucha, DVM, CPT, VC, Charles B. Clifford, DVM, PhD, MAJ, VC, and Don W. Korte, Jr., PhD, MAJ, MSC. GLP Study 88008.

*LAIR Institute Reports are published/available through the Defense Technical Information Service (DTIS).